[12][2], In 2004, Rothberg founded RainDance Technologies, which used droplet-based microfluidics. The promise of a self-administered test in a single tube was irresistibly seductive. The endeavor, which includes a popular caf named after his father and a garden named after his mother, has the feel of a personal micronation. My wife, however, was nine months pregnant, and if there were even a chance our son was infectious we needed to take immediate steps. One of his latest companies, Butterfly Network, recently began. Use of this site constitutes acceptance of our User Agreement and Privacy Policy and Cookie Statement and Your California Privacy Rights. His instincts also highlighted a fundamental distinction between those who coveted the hope that the pandemic might inspire a renewed commitment to collective action on a federal scale, and those who accepted as a fait accompli that America was a nation in which each looked after only his or her own. Whenever his wife was able to be home from the hospital for dinner, the children passed their mothers face in two dimensions around the table. he enlisted the aid of a high-ranking executive at a major Silicon Valley firm who preferred that his involvement not yet be a matter of public record, leaving Rothberg free to play a more expansive, oracular role. As a chemical engineer, biologist, and professor of genetics at Yale University, Rothbergs response to his daughters diagnosis and the lack of satisfactory medical solutions was to search for a cure himself. Ben Rosenbluth, a Homodeus co-founder and floppy-haired recent Yale grad who fell squarely into the category of kids who dont know that what theyre trying to do cant be done, had arrived early to conduct the pilot. Dr. Rothberg is an Ernst and Young Entrepreneur of the Year, is the recipient of The Wall Street Journals First Gold Medal for Innovation, SXSW Best in Show, Nature Methods First Method of the Year Award, the Connecticut Medal of Technology, the DGKL Biochemical Analysis Prize, and an Honorary Doctorate of Science from Mount Sinai. [2], In 2000, 454 Life Sciences was founded as a subsidiary of CuraGen; Rothberg was the CEO of CuraGen at the time. Photograph by Jiajun Wang for The New Yorker, We should look to students to conceive of appropriate, Trump is helping tycoons who have donated to his relection campaign, The coronavirus is likely to reshape architecture. Rothberg pursued a Ph.D. in biology at Yale. I had known from my work at Ion Torrent that if you can leverage Moore's law . Preparation is a tricky process that involves filtering the water, isolating viruses and breaking them open to access their DNA. .galleries:before { Jonathan is that rare person who can do both, with aplomb. I had a need with my daughter. Simplified operating system, simplified use, and a technology that learns as it goes. Wang says his favorite sample came from Corsica, in the Mediterranean. From his invention of revolutionary DNA sequencing technologies to hand-held medical imaging devices, his highly innovative contributions have had enormous impact. This wasnt the only concern. Dr. Rothberg sequenced the first individual human genome (The Watson Genome, Nature), and initiated the Neanderthal Genome Project with Svante Paabo. Hed assumed that the people in charge would get their act together before long, but he swore to himself that he would face the next pandemic with a simple diagnostic platform of his own devising. Identifeye Health (formerly Tesseract Health) was founded in 2018 to build technology at the nexus of radiology and laboratory medicine on the diagnostic tree. The yellowish water should be significantly different from samples of the ocean and freshwater. Led by Founder Dr. Jonathan Rothberg, the Detect team is redesigning the future of healthcare with the power of technology. All of our institutional inventory has gone to hospitals, Rothberg said. The Butterfly iQ ultrasound, developed by Rothbergs startup the Butterfly Network, is seen as a way for individuals to treat themselves at home, including for COVID lung. This summer, they launched the research project by collecting samples from 32 bodies of water across the world. But as the journalism we do is costly, we invite readers for whom The Times of Israel has become important to help support our work by joining The Times of Israel Community. Each company also has a connection to his actual family. 3. [4] In 2012, Rothberg was awarded the Wilbur Cross Medal as a distinguished alumni from Yale University. Rothbergs original plan for 2020 had been to use one of his newer companies, Homodeus, to trawl for genetic evidence of panspermia, the not entirely disreputable idea that life on earth arrived in the form of ancient space dust. Rothberg, who is sensitive to the criticism that his own innovations are merely low-rent versions of better technologies, was determined in this case to make no compromises. At a large biotech conference in February of 2010, during a keynote, he had his largest employee walk in from the back carrying in his arms a machine the size of a desktop printer. Jonathan Rothberg is the founder of Butterfly and has served as the Chairman of New Butterflys board of directors since February 2021. Rothberg told The Times of Israel that the immunosuppressive drug his daughter takes is the result of an initiative that he and his wife sponsored 15 years ago in an attempt to help her. In the US, on an ultrasound, you cant scan yourself, you need a health care professional to guide you remotely, Rothberg said, although self-scans are allowed in other countries, including Italy. I wanted to do all of that with a $2,000 device. They use it to screen for COVID and COVID complications in the brain. He added that the portable scans have been approved by the FDA as well as almost 60 other countries. 4Catalyzer companies include Butterfly Network, Quantum-Si, Hyperfine, Tesseract Health, Liminal Sciences, Detect, AI Therapeutics, and Protein Evolution, Inc.[16]. He taught himself to write code on an early Texas Instruments minicomputer, then sold an inventory-management program to a local tire shop, but wasnt trusted with the house keys. He is best known for inventing and commercializing massively parallel DNA sequencing, which earned him a National Medal of Technology and Innovation from President Obama, the nations highest honor for technological achievement. Sign in to stop seeing this, Sara Netanyahu accosted by protesters at Tel Aviv hair salon, extricated by police, Brides joy turns to sorrow after Elan Ganeles killed driving to her wedding, Hiker discovers 2,500-year-old ancient receipt from reign of Purim kings father, Netanyahu compares Tel Aviv protesters to settlers who set fire to Huwara. Learn more Our philosophy Building companies around a virtuous circle of learning. [18] In September, 2018, Butterfly Network raised $250 million from investors Fidelity, the Gates Foundation, and Fosun Pharma at an estimated $1.25 billion valuation. By Alex Philippidis. The following year, the bull market drove the share price from five dollars to two hundred and fifty in six months. Just that morning, hed been upset to hear that Purdue University, in Indiana, had suspended thirty-six students for attending a party. While Rothbergs children worked out with kettlebells on yoga mats behind us, I took myself through the steps of the test: swirl the swab, which resembles a thin dental pick, in each nostril five times; submerge it into a microcentrifuge tube the size of a sharks tooth; replace the cap, which contains a single white magic beada set of lyophilized, or freeze-dried, reagentsin an open cage structure, and shake until the beads contents dissolve. Together with his wife Bonnie, they created the Rothberg Institute for Childhood Diseases. Rothbergs passion for biotechnology was spurred in part by his daughters rare genetic disorder and, later, a life-or-death scare after the birth of his son Noah in 1999. But I think its useful to think of it in a different frame of mind. And, as he told his investors, their product had long-term post-pandemic potential: what he first called COVID Detect was quickly reimagined as Detect, a flexible diagnostic platform that could easily be retooled to identify cases of the flu, respiratory syncytial virus, and a variety of other maladies. Jonathan was just thinking out loud at all times, and not random thoughts but practical ones, so having him drive a car wasnt really a safe thing to do, he said. Butterfly iQ is a registered trademark of Butterfly Network, Inc. 2023 Blue Cross Blue Shield Association - All Rights Reserved. Many landlubbing researchers have had to drop everything this year to assist with the COVID-19 response, but Jewish-American scientist Jonathan Rothberg started his work fighting the pandemic at sea. Jonathan Marc Rothberg (born April 28, 1963) is an American scientist and entrepreneur. By signing up, you agree to our User Agreement and Privacy Policy & Cookie Statement. So now we have a request. Dr. Rothberg launched Detect in partnership with consumer electronics veteran and now Detect CEO Hugo Barra at the outset of the Covid-19 pandemic with the goal of bringing pathogen testing into the home. [citation needed], Rothberg and his wife Bonnie, a physician who also holds a Ph.D. in epidemiology from Yale, have five children, whom Rothberg often refers to in his speeches. There was, however, good-faith disagreement among experts about how to proceed. "I would be on the top of your rich list if I had skipped graduate school," he quipped to the publication with trademark exuberance. The ocean is a mysterious place, says Elana, now 17 and a rising senior at Choate-Rosemary Hall. Jennifer Rachel Hoos, a daughter of Betsy S. Hoos and Dr. Jeffrey C. Hoos of Woodbridge, Conn., was married on Saturday evening to Jonathan Carl Rothberg, the son of Marilyn Rothberg and. The schools events team had installed Plexiglas-protected card tables in the field houses cavernous gymnasium for sample collection; the effect was of a polling station in an unusually paranoid electoral district. This might seem like a good thing, but there was an argument to be made that a test didnt need to catch an embryonic infection; it only needed to catch the onset, a day or two later, of infectiousnesswhich rapid tests could generally do. The birth of Butterfly iQ, an ultrasound scanner that works with a smart phone. for their antigen test in April, had not yet achieved regulatory approvalthere was no shortage of entrants to the field. would grant his test an emergency approval by June. display: block; Jonathan Rothberg and 10 West San Marino Drive in Miami Beach (Photos via Getty, Venetian Islands Waterfront) A trust linked to a biotech . Options depend on your purchase amount, and a down payment may be required. . Putting the work space on the familys boat instead of at 4Catalyzer in Guilford meant Elana could come along on the familys vacation and still conduct research. As Elana Rothberg was treading in the Arctic Ocean off a Norwegian glacier last summer, a drysuit and sweats staving off the cold, she wondered what could be living in the water around her. Rothberg told The Times of Israel that the immunosuppressive drug his daughter takes is the result of an initiative that he and his wife sponsored 15 years ago in an attempt to help her. For weeks, the team had been talking to various state governments, private colleges, large public-university systems, and major sports leagues. The rollout of such a testing regime, according to Michael Mina, an epidemiologist at Harvard and a co-author of the study, can effectively be akin to a vaccine that was introduced tomorrow. For this reason, many epidemiologists and public-health experts have pushed the F.D.A. I wanted to read his genome. His introduction of massively parallel DNA sequencing technology greatly increased the speed and efficiency of genomic analysis. You can read this a hundred times, but its a personal lesson in how insidious this thing is. Rothberg put the chef up in a motel for two weeks. width: 100px; } Were working with the FDA and other agencies to allow us to allow people to scan themselves, Rothberg said. Dr. Rothberg is a member of the National Academy of Engineering, the Connecticut Academy of Science and Engineering, is a trustee of Carnegie Mellon University and an Adjunct Professor of Genetics at Yale University. By July, it seemed as though the F.D.A. While he took videoconference meetings one day, I was joined on the sundeck by his intern, Isaac Bean, a self-taught molecular biologist and maker whod answered a Twitter call for help, spoken to Rothberg an hour later, and driven from Colorado Springs to Savannah the next day. [1] He works and resides in Guilford, Connecticut. The schools total population was only around six thousandsmall enough, the schools testing task force believed, that it could adopt the sort of testing regime that Rothbergs kit would make possible. Dr. Jonathan Rothberg is the founder of multiple life science and medical device companies including Butterfly Network, Hyperfine and the 4Catalyzer incubator.
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