Apoquel starts working within 4 hours of administering the first dose and controls itching within 24 hours. May be used with other common medications. Feline idiopathic ulcerative dermatosis treated successfully with oclacitinib. She would be a scratching mess without it. Apoquel has been used safely with many common medications including parasiticides, antibiotics and vaccines. Submit Office Orders & Patient Prescriptions. The innovative formula of the drug allows you . This content is intended for counseling purposes only. U.S. Food and Drug Administration Center for Veterinary Medicine 7500 Standish Place Rockville, MD 20855 www.fda.gov . Weve also been able to start rehabbing back into work. Apoquel is a dog allergy medicine used to treat and control chronic manifestations of allergic and atopic dermatitis in dogs. Commonly prescribed for: Manage inflammation in diseases or conditions in which the immune system has a significant role, Therapeutic Class: Synthetic Corticosteroid Hormone. 17. Therefore, the recommended initial dosage for dogs 6.6-9.9 lbs is of a 3.6 mg tablet twice daily. If your horse has "classic" RAO, he may have more difficulty in the barn, and need to be kept outside 24/7.3: The Supplements: Studies have shown that horses with Asthma benefit from supplements with Omega 3 fatty acids. Vet J 2016;207:29-37. Really? A blinded, randomized, placebo-controlled trial of the safety of oclacitinib in cats. She still has her mane this year- which is good! 1,2 The #1 prescribed medicine for allergic itch in dogs. Right now he is on an Aservo Inhaler but I dont see any improvement and he is getting real tired of the application process. She added, "Studies show that omega-3 fatty acids help horses with equine asthma. Pollen and other plant-based aeroallergens are the source of their distress, and they fare much better inside a well-ventilated barn. Pruritus is a common clinical sign in allergic skin diseases. The recommended Apoquel (main ingredient, oclacitinib) dosage for dog use is as follows: The recommended dosage is 0.18 to 0.27 mg of oclacitinib per pound of body weight, for the first 14 days. J Biol Chem 2007;282(28):20059-20063. Horse dosing is 5 pills. Efficacy of oclacitinib (Apoquel) compared with prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis in client-owned dogs in Australia. There are two types of this condition, summer-pasture-associated and classic recurrent airway obstruction (RAO). For example: 1,000 lb horse X 10 mg/lb = 10,000 mg. One of the things the trials found on using apoquel with horses is that they need a relatively small dose. Apoquel tablets are scored to be halved to ensure that the ingredients are equally distributed. If signs . The recommended Apoquel dosage for dogs is 0.18 to 0.27 mg per lb of body weight (0.4-0.6 mg/kg) once a day. Dosage and administration For oral use. Clenbuterol dilates the airways, and may improve air flow, but it doesn't treat the inflammation associated with the disease. In cats, this medication can cause excitement rather than sedation. The Janus kinases (Jaks). The anti-inflammatory/immunosuppressive response is confined almost exclusively to the lungs, avoiding a bodywide effect, says Fultz. Discount Prices on Pet Supplies, Nexgard, Bravecto, Trifexis, Simparica TRIO, Apoquel, and more. Anecdotal reports indicate that oclacitinib is not very effective in managing recurrent and/or chronic otitis and interdigital furunculosis associated with allergies, and a sudden loss of efficacy is often associated with bacterial or. Adverse events were reported in less than 5% of dogs, including urinary tract infection, vomiting, otitis, pyoderma, and diarrhea.9 A subsequent study concluded that there is no increased risk for urinary tract infections.10, The efficacy of oclacitinib was also compared to that of other drugs such as prednisolone and cyclosporine. In the first pilot study, oclacitinib (0.4 to 0.6 mg/kg, q12h for 14 days, then q24h for 14 days) was used to treat pruritus in cats with non-flea, nonfood-induced hypersensitivity dermatitis. Interleukin-31: its role in canine pruritus and naturally occurring canine atopic dermatitis. Stay on top of the most recent Horse Health news with, If interested in adopting this horse, please submit an Adoption Inquiry via our website: Allaboutequine dot org. This is totally random but figured Id mention it since I had no idea till I saw someone mention itZoetis has a rewards program and Apoquel is one of the drugs on it. You can give your dog Apoquel with or without food. Please select your state below. Vet Dermatol 2016;27(Suppl 1):84 (abstract). Maintaining Your Horses Weight During the Winter, Special Report: Preventing 3 Common Equine Joint Issues, JACKSON- Gelding/Bay/Mustang (Nevada) - Project/Ready for Training, JENNINGS Gelding/Cremello/Mustang (BLM) Ridable (Green), recent study evaluating almost 400 potential allergens, BONNIE: Sorrel Mustang Mare Non-Riding Companion Only. This drug has been used in dogs with some pretty fabulous results. Drake GJ, Nuttall T, Lpez J, et al. Apoquel Dosage. The drug is primarily used as a tranquilizer to calm anxious pets, especially dogs and horses, according to DailyMed. Her lifelong love of horses motivated her to adopt her college care horse, Claire, upon graduation. Thereafter the dose should be reduced to once daily for maintenance. Apoquel has been a game changer, however. So I think cost becomes dependent on that. Posted by Lucile Vigouroux | May 4, 2022 | Article, Diseases and Conditions, Farm and Barn, Hives & Skin Allergies, Horse Care, Medications, Nutrition, Seasonal Care, Skin Problems. APQ-01043R3, halved to ensure that the ingredients are equally distributed. Equine Regenerative Therapies for Managing Arthritis in Horses, Infographic | 12 Smart At-Home Biosecurity Practices for Horse Owners, Infographic | How To Keep Your Horses Joints Healthy. Alternatively, your veterinarian may be able to show you some techniques. 29. Apoquel is the brand name of oclacitinib, a dog medication designed to relieve itching associated with allergies in dogs, particularly canine atopic dermatitis. This regimen may work better because oclacitinib has a short half-life of 4 hours. Oclacitinib can be given without food and may be discontinued without tapering. All rights reserved. This treatment option is FDA approved for equine asthma, and is very safe with no known side effects. When your dog (cat, horse, child) reacts violently to everyday things like; flea saliva (even from one solitary flea) . But you're making a deal with the devil when you use these . Thats def not nothing but its not insane. Vet Dermatol Apoquel Dosing Chart For Dogs Dexamethasone commonly is used in horses to treat allergic reactions such as respiratory allergies, chronic obstructive pulmonary disease (heaves), hives, itching and inflammatory diseases including arthritis. And some can got a lower dose or a further spread out dose. Genome Biol 2004;5(12):253. Powered by Discourse, best viewed with JavaScript enabled. The recommended dosage of Apoquel 3.6mg tablets is 0.18 to 0.27 milligrams per pound of body weight. The frequency of urinary tract infection and subclinical bacteriuria in dogs with allergic dermatitis treated with oclacitinib: a prospective study. Recently, researchers have delved into the causes and consequences of what now falls under the umbrella term equine asthma. KER offers EO3, which contains the omega-3 fatty acids DHA and EPA. Because insects are omnipresent in the horses environment at least some portion of the year, IBH is particularly labor-intensive to manage. This makes it a common site for the bodys expression of allergic reactions. Apoquel is an anti-itch tablet given twice daily for the first . (https://www.zoetispetcare.com) I get $9 back for every 30 pills I order, it goes onto a Mastercard debit card that can only be used at a vets office but I spend plenty of money there. 28. Let's look at the differences between these two medications, as well as some other treatment options for your dog's allergies. Vet Dermatol 2016;27(Suppl 1):100 (abstract). A blinded, randomized clinical trial comparing the efficacy and safety of oclacitinib and ciclosporin for the control of atopic dermatitis in client-owned dogs. Some states restrict the information we may provide about controlled substances. A follow-up study assessed the long-term safety, efficacy, and quality of life of oclacitinib-treated dogs. Barns can also have noxious gases from the ammonia in urine. Give one chewable per month to the dog. In the first 2 randomized, double-blinded, placebo-controlled clinical trials, it was shown that oclacitinib, given at a dose of 0.4 to 0.6 mg/kg q12h, induced a rapid reduction in pruritus and treatment success in 62.3% to 67% of treated cases within 7 to 14 days.7,8 Treatment success was based on reductions from baseline of at least 2 cm on the owner-assessed visual analog scale and at least 50% on the clinicians Canine Atopic Dermatitis Extent and Severity Index (CADESI-02). Merck & Co., Inc., Rahway, NJ, USA (known as MSD outside of the US and Canada) is dedicated to using the power of leading-edge science to save and improve lives around the world. A native of Japan, Dr. Hensel subsequently moved to Basel, Switzerland, where she opened a veterinary dermatology practice in 2014. Find out more. Collard WT, Hummel BD, Fielder AF, et al. Insect and pollen season is here. holy crapola batman- just had to put my dog back on it (Hes usually on it April through Nov but with the weird weather we got away with waiting until July thankfully) and saw the price increase- yikes! Cost is <$50/month, its easy, and its usually very effective. Log in to fill, refill or renew the medication prescribed by your veterinarian. J Vet Pharmacol Ther 2014;37(3):279-285. Serious side effects include seizures, abnormal breathing, incoordination, muscle tremors, and coma. All product and company names are trademarks or registered trademarks of their respective holders. Allergies can develop at any time, in any horse, and seemingly for any reason. A newer prescription drug, Apoquel (oclacitinib) has recently hit the market and might prove useful for allergic horses. See full Excede for Swine Prescribing Information. In a 3-week trial, the combination of oclacitinib and cyclosporine did not show an increased risk for adverse effects. Oclacitinib (APOQUEL) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Little PR, King VL, Davis KR, et al. Helpful steps you can take include providing full-body fly apparel, applying fly spray liberally, avoiding turnout at dusk and dawn, and using fans in stalls to disrupt insect flying patterns. Fortunately, these side effects are relatively uncommon. Zyrtec: The human antihistamine may be beneficial in a small proportion of horses with Equine Asthma. While efficacy was comparable to that observed in the previous studies, significant positive effects on the dogs quality of life were observed in >91.5% of cases after 630 days. Intradermal allergy testing is the gold standard for this and involves a veterinary dermatologist subcutaneously injecting very small quantities of potential allergens into a clipped patch of the horses neck. Levy BJ, Linder KE, Olivry T. The role of oclacitinib in the management of ischaemic dermatopathy in four dogs. Avoiding Allergies Many of these cytokines bind to cytokine receptors that have JAK enzymes associated with their cytoplasmic portion. Apoquel is a prescription dog allergy medicine used for the control of itch associated with allergic dermatitis and control of atopic dermatitis in dogs 12 months and older. Rarely, dogs on Apoquel develop new skin masses; however, a long-term study found no association between Apoquel and the development of malignant cancer. The Feed: One of the most common recommendations for managing Equine Asthma has always been to stop feeding hay. Side effects have been rarely seen and documented, but the most common occurrences have been mild vomiting and diarrhea. With an online account, access our extensive formulary or over 40,000 unique items - 24 hours a day, 7 days a week. Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis. Apoquel is not FDA approved to use twice daily longer than 14 days. Meaning, if a 100lbs dog gets 16mg (1 pill), a horse does not need 160mg (10 pills). Webcast | Cosgrove SB, Wren JA, Cleaver DM, et al. Cosgrove SB, Cleaver DM, King VL, et al. While oclacitinib is a very effective and fast-acting antipruritic drug, the decision of when to use it depends on various factors. Option 4 is an oral tablet called Apoquel. Depending on the size of a cat and the condition being treated, a veterinarian may elect to alter the dosage. The pharmacokinetics of oclacitinib maleate, a Janus kinase inhibitor, in the dog. Apoquel delivers onset of relief within 4 hours and effectively controls itching within 24 hours. The downside is that it can cause laminitis and can suppress their immune system. Dosage Chart Assuming you cannot contact your vet: For hives or possible allergic airway disease (heaves), for a 1000 lb horse, give 5-10 tabs of 25mg diphenydramine crushed up and mixed in water and dosed in a syringe orally (by mouth). Apoquel is a non-hormonal drug for dogs, used for dermatitis of various etiologies, which are accompanied by itching. A blinded, randomized, placebo-controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel) in client-owned dogs with atopic dermatitis. A newer prescription drug, Apoquel (oclacitinib) has recently hit the market and might prove useful for allergic horses. Cosgrove SB, Wren JA, Cleaver DM, et al. Vet Dermatol 2018:29:371 (abstract). However, a small subcategory of asthmatic horses suffer from pasture-associated equine asthma. Apoquel Dosage in Dogs Apoquel tablets for dogs comes strengths of 3.6mg, 5.4 mg and 16mg of oclacitinib per tablet. Vet Dermatol 2013;24(6):587-597, e141-142. Not really cheap any way you shake it, but considering that she was on zyretc, dex, smarthbreathe ultra, respi-free previously. Allergies primarily affect the immune, respiratory, and integumentary (skin) systems and, if unmanaged, can seriously impact an animals performance and well-being. Initially, the recommended dose of 0.4 to 0.6 mg/kg should be given twice daily for up to 14 days. . Quartering tablets is extra-label use. Dosage and treatment schedule The recommended initial dose is 0.4 to 0.6 mg oclacitinib/kg bodyweight, administered orally, twice daily for up to 14 days. Because one of mine had similar food allergies and I was told the serum would not address that. APOQUEL may be administered with or without food. 13. Oclacitinib in feline nonflea-, nonfood-induced hypersensitivity dermatitis: results of a small prospective pilot study of client-owned cats. The Janus kinases (Jaks). Rectal Prolapse in Dogs and Cats. Before your vet administers immunotherapy, though, you must identify your horses respiratory and skin allergies. Adv Vet Dermatol 2017;8:192-198. Gadeyne et al compared prednisolone and oclacitinib at recommended doses and found that both drugs resulted in similar rapid effects with regard to pruritus and dermatitis reduction.11 Little et al compared oclacitinib to cyclosporine. Like other medications in its class, it may also be used off . Levy BJ, Linder KE, Olivry T. The role of oclacitinib in the management of ischaemic dermatopathy in four dogs. RELATED CONTENT | Infographic: Equine Allergies. Oclacitinib (APOQUEL) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Vet Dermatol 2019;30(2):87-90. Apoquel tablets provide quick relief for itching and inflammation. The most common side effect is lethargy, dry mouth, and urinary retention. For atopic and allergic dermatitis, Apoquel may be given to dogs at a dosage of 0.18 - 0.27 mg/lb. The Vet had put her on Apoquel as an initial dose for 10 days tapering off. Allergies primarily affect the immune, respiratory, and integumentary (skin) systems and, if unmanaged, can seriously impact an animals performance and well-being. We have had variable results with this treatmet. Researchers have proven flaxseed reduces skin lesions in IBH horses (ONeill et al., 2002). Once you have the horse's symptoms under control, you can try re-introducing hay. A newer prescription drug, Apoquel (oclacitinib) has recently hit the market and might prove useful for allergic horses. 13. Gonzales AJ, Humphrey WR, Messamore JE, et al. The compounded medications featured in this content have been prescribed and/or administered by prescribers who work with Wedgewood Pharmacy. She reports choosing Apoquel over corticosteroids in several of her allergic patients that are also at risk for developing laminitis. Its an annoying pill schedule to keep track of, but my boarding barn has been great about it. Aymeric E, Bensignor E. A case of presumed autoimmune subepidermal blistering dermatosis treated with oclacitinib. This product came to the market in the US in Fall 2020. Vet Dermatol 2015;26:297 (abstract). Pre-slaughter withdrawal time is 14 days following the last dose. Efficacy of oclacitinib (Apoquel) compared with prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis in client-owned dogs in Australia. I paid $250 for 100 pills (thats 20 5-pill doses). Unlike some other allergy. This treatment is typically effective, but the steroid is still absorbed into the body, which can result in laminitis risk, similar to Option 1. Cochet Faivre N, Degorce-Rubiales F. Clinical eosinophilic popular dermatitis associated with histological eosinophilic granuloma rapidly responsive to oclacitinib in an adult Labrador retriever. The recommended dose of Apoquel for dogs is 0.18 to 0.27 mg per pound of body weight. Vercelli A, Cornegliani L. Use of oclacitinib in treatment of canine idiopathic ear tip vasculitis. That's why dosage is usually tapered down to the lowest effective dose. These reports suggest the potential use of oclacitinib in other diseases; however, it cannot be stressed enough that the use of oclacitinib in these diseases is an off-label use. Although no studies of pharmacokinetics in cats have been published, oclacitinib is well tolerated and seems to be safe when used in cats at 1 or 2 mg/kg q12h for 28 days. $ 78.30 - $ 245.00. Vet Dermatol 2019;30(2):110-e30. Some dogs exhibit increased pruritus when the dosage is reduced to once daily. After completing a doctorate thesis and a rotating internship at the University of Zurich, Switzerland, he moved to the United States, where he completed a 3-year veterinary dermatology residency at the University of Georgia in 2004. More severe ones, however, can truly take a toll on your horses health and make him miserable. It is no surprise we see this omega-3-rich plant with anti-inflammatory and antioxidative properties in many skin and allergy supplements. These can be severe and lead to a life-threatening, airway-blocking, whole-body reaction called anaphylaxis. See how Apoquel works differently from steroids and cyclosporines, Discover how Apoquel can relieve allergic itch through an 8-week food trial, Hear from your peers about why Apoquel is their first choice for allergic itch relief, Explore the United States of Apoquel to see how Apoquel has benefited veterinarians in your region, Hear real stories of allergic itch relief from pet owners, See how Zoetis Petcare Rewards can benefit your practice, Informational resources for you to download and utilize within your practice, Provide additional information about Apoquel to pet owners with these resources, Continue therapy once daily (SID) thereafter for maintenance. 25. A blinded, randomized, placebo-controlled trial of the efficacy and safety of the Janus kinase inhibitor oclacitinib (Apoquel) in client-owned dogs with atopic dermatitis. Im not dealing with food allergies but both the company and the vet did not recommend allergy shots for my mare. The dosage will depends on your dog's weight. Transdermal applicator that gives easy & accurate dosing every time. Innovation is constantly occurring in the field of immunotherapy. As the only FDA-approved equine PSGAG (polysulfated glycosaminoglycan) for degenerative joint disease (DJD) in horses, Adequan i.m. Vet Dermatol 2015;26(1):23-30, e7-8. Frank RK, Galvan BA, Schoell AR, et al. I often recommend switching your Asthma horse off of regular hay and trying a period of hay-replacement to see if it helps. White believes that while further research in horses is warranted, veterinarians should consider latex exposure a potential risk to equine respiratory health. Apoquel For Dogs: Dosage Apoquel comes in three tablet sizes: 3.6mg, 5.4mg, and 16mg. This option has somewhat fewer risks than option 1, has a higher initial cost ($1,000 for the nebulizer mask), but a lower monthly cost- $20-$40/month. In the past 5 years, however, oclacitinib (Apoquel; ), a Janus kinase (JAK) inhibitor, has become another important drug in the management of allergic pruritus. Saridomichelakis MN, Olivry T. An update on the treatment of canine atopic dermatitis. I was one of the veterinarians involved in early field trials for Apoquel in horses. Avoid storing hay in the same barn as sensitive horses. Veterinarians are especially wary of administering corticosteroids to allergic horses that suffer from pituitary pars intermedia dysfunction, insulin dysregulation, and/or equine metabolic syndrome, because these conditions are also risk factors for laminitis. Equine Nutrition FAQ Series, sponsored by Purina Animal Nutrition. Left untreated, these conditions can not only cause discomfort but also lead to raw, broken skin that allows bacteria to invade and infect. Avoid giving the medicine twice daily long-term. While easy to perform, Fultz says its not always accurate at predicting the exact allergens. 15. Binding of these cytokines to their receptors activates the JAK-STAT (signal transducers and activators of transcription) pathway, which leads to further cytokine production.1 In recent studies, IL-31 has been shown to play an important role in pruritus, and elevated serum levels of IL-31 have been found in many atopic dogs.2, There are 4 JAK families in mammals: JAK1, JAK2, JAK3, and TYK2. Oclacitinib preferably inhibits JAK1 and, to a lesser degree, JAK3, resulting in decreased activity of JAK1-dependent cytokines involved in allergy and inflammation (IL-2, IL-4, IL-6, and IL-13) as well as pruritus (IL-31).4. Option 4 is an oral tablet called Apoquel. 9. While relatively safe for use in most horses, these potent anti-inflammatory drugs can cause a serious potential side effect in some individuals: an increased risk of developing the debilitating hoof disease laminitis. The concentration of the drug is 500 mg/ml. It generally reduces itching very quickly within 24 hours and is felt to be as effective as corticosteroids. Many allergic reactions are evident as a mild case of transient hives. Its anti-inflammatory and expectorant properties can soothe irritated lung tissues and help to expel mucus.Licorice root should not be fed to pregnant mares. I did not know about this, but considering Im going through apoquel at a reasonable rate this sounds like it would be worth signing up for. Panteri A, Strehlau G, Helbig R, et al. Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age. The most common side effects associated with Apoquel are vomiting, diarrhea, and lethargy. So lets review why allergies happen, how they affect your horses body, and how to treat themor, better yet, how to avoid them altogether. Dosing Chart Contraindications Because many respiratory allergies come from the dust in hay and bedding, veterinarians generally recommend maximizing fresh-air time through turnout. 12. Six adult horses with a mean weight of 528 kg were administered a single dose of 0.5 mg/kg oclacitinib maleate. If your horses allergies are seasonal, talk to your veterinarian about steps you can take to stay ahead of them. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. These animals require the opposite regimen. Drake GJ, Nuttall T, Lpez J, et al. Aymeric E, Bensignor E. A case of presumed autoimmune subepidermal blistering dermatosis treated with oclacitinib. Vet Dermatol 2019;30(1):17-e6. In a 3-week trial, the combination of oclacitinib and cyclosporine did not show an increased risk for adverse effects.13, Anecdotal reports indicate that oclacitinib is not very effective in managing recurrent and/or chronic otitis and interdigital furunculosis associated with allergies, and a sudden loss of efficacy is often associated with bacterial or Malassezia overgrowth.14 Sudden withdrawal from oclacitinib can also result in a rapid return of clinical signs, which sometimes appear more severe than before treatment.15, Most recently, it was suggested that the treatment strategy for canine atopic dermatitis might need to be adjusted. On the label for dogs, Apoquel is used every 12 hours for the first 14 days of use, then backed down to dosing every 24 hours once a day. If you struggle to get your dog to take tablets, you can try hiding it in their food, or wrapping it in a tasty piece of meat. Pet owners should visit ZoetisPetcare.com for product info, rewards and support. Fukuyama T, Ganchingco JR, Bumer W. Demonstration of rebound phenomenon following abrupt withdrawal of the JAK1 inhibitor oclacitinib. Dr. Nao Hensel obtained her doctor of veterinary medicine degree from Colorado State University in 2010. In the first pilot study, oclacitinib (0.4 to 0.6 mg/kg, q12h for 14 days, then q24h for 14 days) was used to treat pruritus in cats with non-flea, nonfood-induced hypersensitivity dermatitis. The dose of APOQUEL (oclacitinib maleate) tablets is 0.18 to 0.27 mg oclacitinib/lb (0.4 to 0.6 mg oclacitinib/kg) body weight, administered orally, twice daily for up . There are a few medication protocols for horses with Equine Asthma. 2. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. Diphenhydramine can alter the results of skin allergy testing; discontinue this medication at least 2 weeks before testing. Her asthma had gotten so bad I thought I wouldnt be able to ride her again, but now we are back to w-t-c. She is down to every other day. She then completed a 1-year rotating small animal internship in Massachusetts followed by a 3-year veterinary dermatology residency in Georgia. Interestingly, the results suggest that oclacitinib has immunosuppressive properties, but only at a higher dosage than that approved on the label.30. @vxf111 we were told the same thing for food allergiesthat they did not make serums fot them because they were not very effecttive and the the expectation was that the allergen be removed from the diet. Ortalda C, Noli C, Colombo S, et al. There are 4 JAK families in mammals: JAK1, JAK2, JAK3, and TYK2. Oclacitinib preferably inhibits JAK1 and, to a lesser degree, JAK3, resulting in decreased activity of JAK1-dependent cytokines involved in allergy and inflammation (IL-2, IL-4, IL-6, and IL-13) as well as pruritus (IL-31). The mare luckily didnt have a lot of food allergies and eliminating flax wasnt a big deal. Freedom of Information Summary NADA 141-345 More severe ones, however, can truly take a toll on your horses health and make him miserable. This site is intended for US animal healthcare professionals. 30. 28. Apoquel reduces dog itch, and also decreases inflammation, redness, or swelling of the skinso your dog feels better as quickly as possible What is Apoquel Tablet? That was 5-6 years ago now. This medication may be a very good option for minis, since the costs will be much lower. Skin allergies can also cause pruritus (itching) and associated hair loss. Use of oclacitinib (Apoquel; Zoetis) for treatment of cutaneous mastocytosis in a cat. It is most risky in horses that have metabolic disease like Equine Metabolic Syndrome (insulin resistance), PPID (cushings), or those that are overweight. Interestingly, the results suggest that oclacitinib has immunosuppressive properties, but only at a higher dosage than that approved on the label. In more severe cases, Apoquel can be given twice per day. 1800PetMeds is your online pet store offering discount prices on pet supplies, medications, vitamins and supplements for your pet. Nevertheless, these data should be taken with caution, and only as an approximation, because there is no basic information on the . Hay replacement consists of any of the following: a complete pelleted diet, soaked alfalfa cubes, hay pellets, or possibly a bagged forage product like Chaffhaye. Works on all common sources of allergens. These reports suggest the potential use of oclacitinib in, While oclacitinib is a very effective and fast-acting. APOQUEL may be administered with or without food. Even though the drug is currently labeled for use in dogs (with allergic dermatitis), initial studies show that horses absorb it well, Fultz says. These inhaled substances can trigger an allergic response that causes narrowing of the airways, mucous secretion, and cough., Luckily, minimizing common allergens in your horses environment could suffice to restore his comfort and breathing. Haugh IM, Watson IT, Menter MA. Luckily most of her allergies appear to be insect-based and she responds very well to the serum for that. Noli C, Matricoti I, Schievano C. A double-blinded, randomized, methylprednisolone-controlled study on the efficacy of oclacitinib in the management of pruritus in cats with nonflea nonfood-induced hypersensitivity dermatitis. Acepromazine affects animals and humans by depressing the central nervous system.